Cryptococcosis caused by the Cryptococcus neoformans–Cryptococcus gattii complex is an important opportunistic infection in people with immunodeficiency, including in the haematology/oncology setting. This may manifest clinically as cryptococcal meningitis or pulmonary cryptococcosis, or be detected incidentally by cryptococcal antigenemia, a positive sputum culture or radiological imaging. Non-Candida, non-Cryptococcus spp. rare yeast fungaemia are increasingly common in this population. These consensus guide-lines aim to provide clinicians working in the Australian and New Zealand haematology/oncology setting with clear guiding principles and practical recommenda-tions for the management of cryptococcosis, while also highlighting important and emerging rare yeast infections and their recommended management.
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